- The common causes of hyperventilation resulting in respiratory alkalosis are given in the Table (click here).
- The rise in CSF pH that occurs with acute respiratory alkalosis is associated with a significant reduction in cerebral blood flow that may lead to lightheadedness and impaired consciousness. Generalized membrane excitability can result in seizures and arrhythmias. Symptoms and signs of acute hypocalcemia. may be evident from the abrupt fall in ionized calcium that can occur.
- Chronic respiratory alkalosis is usually asymptomatic since a normal pH is well defended by compensation.
- The rise in pH from acute respiratory alkalosis can cause a reduced ionized calcium, a profound hypophosphatemia, and hypokalemia
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- Treatment of respiratory alkalosis should focus on identifying and treating the underlying disease. In ICU patients this may involve changing the ventilator settings to decrease ventilation.